Anjali began her journey in the entertainment industry as a model before making her silver screen debut in the Telugu thriller Photo (2006). Her breakthrough came with the critically acclaimed Tamil film Kattradhu Thamizh (2007), which earned her the Filmfare Award for Best Female Debut – South .

: She grew up in a Telugu-speaking family with two brothers and a sister. Her parents originally aspired to be actors themselves and often state they "realized their dreams" through her career. Modeling Roots