When you quit Prototype 2 , press Win + R and type explorer to restore your desktop. This frees up nearly 600MB of RAM on Windows 10/11.

You can force the game to run at a lower, non-standard resolution to boost FPS. Right-click Prototype 2 in your Steam Library. Properties Launch Options

Render

If you manage to get into the game menu, use these specific settings to ensure the config stays stable:

periodically to refresh the RAM allocation or closing background apps like Chrome. Steam Community Verdict for Low-End Users